연구제목

Cybersickness Prevention and Mitigation in Virtual Reality for Healthy Volunteers

연구요약

Background: People use virtual reality (VR) technology to play games, socialize, work, or receive medical care. Some people have "cybersickness" after using VR. Cybersickness is similar to motion sickness. Symptoms include eye strain, nausea, dizziness, or headache. The symptoms are usually mild and go away after the person stops using VR. New software called Motion Reset is being designed to reduce symptoms of cybersickness during VR use. Objective: To see if Motion Reset software can reduce cybersickness in people using VR. Eligibility: Healthy adults aged 18 to 60 years. Design: Participants will have 1 clinic visit that will last about 1 hour. They will answer questions about how they are feeling. They will learn how to use the VR headset and the handheld game controllers. The study will be broken into 2 parts. For the first part, participants will be assigned to 1 of 3 groups: Group 1 will participate in a VR experience designed to prevent cybersickness. They will view screens and move around while they press buttons on a controller. Group 2 will participate in a VR experience that is not designed to prevent cybersickness. They will view screens and move around while they press buttons on a controller. Group 3 will have no VR experience. Participants will complete 2 questionnaires about their experiences in the first part of the study. For the second part, all participants will spend up to 20 minutes playing a commercial VR game called Jurassic World Aftermath. Every few minutes, they will be asked if they are experiencing discomfort. After playing the game, participants will complete 12 questionnaires about their experience....

연구의뢰자

National Human Genome Research Institute (NHGRI)

연구모집현황

NOT_YET_RECRUITING

임상시험의 목적

PREVENTION

ClinicalTrials.gov 등록번호

NCT06552754

추가 연구 번호

최신갱신일

2025-06-11

연구종료일

2026-05-01

연구 버전 기록

실시기관명

facility: Iowa State University
city: Ames
state: Iowa
zip: 50011
country: United States
geoPoint: {lat=42.03471, lon=-93.61994}

facility: National Institutes of Health Clinical Center
city: Bethesda
state: Maryland
zip: 20892
country: United States
contacts: [{name=NIH Clinical Center Office of Patient Recruitment (OPR), role=CONTACT, phone=800-411-1222, phoneExt=TTY dial 711, email=ccopr@nih.gov}]
geoPoint: {lat=38.98067, lon=-77.10026}

연구대상 상태/질환

Healthy Volunteers

Virtual Reality

대상질환

제품명(코드명)

활성대조약 여부

대조약 여부

위약 여부

대조약

-

중재/치료

type: BEHAVIORAL
name: Motion Reset
description: virtual reality-based experiential, sensory intervention
armGroupLabels: [Intervention: Motion Reset]

type: BEHAVIORAL
name: Placebo
description: virtual reality-based experiential, sensory experience without intervention
armGroupLabels: [Placebo experience]

중재 방법

연구종류

INTERVENTIONAL

임상시험단계

NA

배정

RANDOMIZED

중재모형

PARALLEL

눈가림대상자

PARTICIPANT

중재군명

중재군 유형

label: Intervention: Motion Reset
type: EXPERIMENTAL
description: Participate in virtual reality activities
interventionNames: [Behavioral: Motion Reset]

label: No intervention
type: NO_INTERVENTION

label: Placebo experience
type: PLACEBO_COMPARATOR
description: Participate in virtual reality activities
interventionNames: [Behavioral: Placebo]

중재군 수

0

중재군 별 설명 및 등록 환자수

중재군 목표대상자 수

0

기관소재지

실시기관 전화번호

연구참여기관

국가

환자모집국가

최초 연구대상자 등록일

2025-06-16

상세내용

대상자 선정 및 제외기준

* INCLUSION CRITERIA: In order to be eligible to participate in this study, an individual must meet all of the following criteria: * Provision of signed and dated informed consent form * Stated willingness to comply with all study procedures and availability for the duration of the study * Aged 18-60 * Ability to read, speak, and write in English * Normal or corrected-to-normal hearing * Normal vision or corrected-to-normal without use of glasses. Contact lenses for corrective purposes are acceptable. Ability to read, speak and write in English is a requirement because the VR-based study materials and assessment are only available in English and several of the key questionnaires for the study are not validated in other languages. EXCLUSION CRITERIA: An individual who meets any of the following criteria will be excluded from participation in this study: * Reporting motion sickness propensity of 0 or 10 on a 0-10 scale where 0 =never experience motion sickness and 10 = experience motion sickness very frequently (self-assessed by participants). * Reporting a history of photo-sensitive seizure disorders, vestibular disorders and/or other conditions that may make participants prone to nausea, dizziness, vertigo, ataxia, or incoordination. * Known pregnancy * Reporting current use of medication or supplements that inhibit nausea, e.g., Zofran/ondansetron, Phenergan/promethazine

참여 가능한 연령 하한

18 Years

참여 가능한 연령 상한

60 Years

참여 가능한 표준 연령

ADULT

대상자 포함기준 성별

ALL

건강인 참여 여부

NO

실제 대상자수

150

기존 목표대상자 수(실제)

0

최종 연구대상자 수

0

최종 시험대상자 선정일

시험대상자 > 분석대상군

시험대상자 > 인구학적 정보

주요결과변수

measure: self-reported cybersickness
description: Assessed on numerical scale
timeFrame: during and after VR use

보조결과변수

measure: discontinuation of VR use
description: decision to discontinue VR during active session
timeFrame: during VR use

주요 평가 > 1차 평가변수 결과

최종 주평가변수 수집 완료일

2026-05-01

임상시험결과요약

연구책임자 전화번호

연구책임자 주소

연구실무담당자 성명

연구실무담당자 직위

연구실무담당자 전화번호

name: Susan J Persky, Ph.D.
role: CONTACT
phone: (301) 451-1268
email: NihVRStudy@nih.gov

연구실무담당자 기관명